FACULTY

 

MOSHE ABELES

 

Phone: 03-5317755

Fax: 03-5352184
email: moshe.abeles@mail.biu.ac.il

 

Lab: Higher Brain Functions Lab

 

The Leslie and Susan Gonda
Multidisciplinary Brain Research Center
Bar Ilan University
Ramat-Gan 52900
Israel

 


 

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RESEARCH INTERESTS

 

The way in which perceptions, memories, intentions, etc., are represented in the nervous activity of the brain is not known. The main focus of this field of investigation is to discover these representations and understand the neuronal mechanism which generates them. This is a combined effort including recording the activities of several nerve cells in parallel from appropriate places in the brain of behaving monkeys, devising new mathematical methods for analyzing the data, and verifying the theory by constructing (by way of simulations) neural networks which mimic the postulated brain processes.

So far the results indicate that the prevailing view about coding by enhanced neural activity is only part of the truth. The exact timing of nerve cell activity contains much of the information about what is happening in the brain. This timing can be "read" by neurons due to their sensitivity to synchronized activation. This same property also serves as the basic mechanism by which exact timing is generated. A neural-network known as a synfire chain can both read and generate such well -timed activities. The experimental results support the synfire hypothesis and extend it by suggesting that activity reverberates in such synfire modes. We assume that reverberating synfire chains in different brain locations can resonate with each other, thereby generating a unified "mental" experience.

 


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EDUCATION AND AWARDS

 

1956-1960 The Hebrew University, Jerusalem M.Sc. Physiology

1960-1966 The Hebrew University, Jerusalem Ph.D. Neurophysiology

1966-1968 Johns-Hopkins Univ., Baltimore Post Doc. Biomedical Engineering

 

1968 Back prize for 3 papers on excitability of EEG synchronizing and desynchronizing neurons

1971 I.A.P.I. First prize for work on "Computer aided analysis of nerve cell activity"

1980 Dr. Mona and Dr. Ernest Spiegel Chair of Neurophysiology

1980 Visiting professor, Universite de Lausanne

1986 Visiting professor, University of Pennsylvania

1986 Johns Hopkins Society of scholars

1996 Teva founders prize for outstanding work in brain research

1999 Miller visiting professor, UC Berkeley, USA 2004 Emet prize, Israel

2004 - Emet prize, Israel

1997-2000 USA-Israel Binational Science Foundation (with G. L. Gerstein, Philadelphia)

1998-2001 GIF (with A. Aertsen, Freiburg)

2000-2006 Center of Excellence of Israel Science Foundation
(with H. Bergman, H. Sompolinsky, N. Tishby & E. Vaadia, all from Jerusalem).

2002-2005 GIF (with A. Aertsen, Freiburg)

2003-2005 Horowitz fund

2004-2008 DIP (with M. Teicher, T. Flash and T. Geisel, Goetingen)


 

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SELECTED PUBLICATIONS

 

Abeles M. Local Cortical Circuits: An Electrophysiological study. Springer, Berlin, 1982

Abeles M. Corticonics: Neural circuits of the cerebral cortex. Cambridge University Press, New-York, 1991

Ben-Shaul Y., Drori R., Asher I., Stark E., Nadasdy Z., and Abeles M. Neuronal activity in motor cortical areas
reflect the sequential context of movement. J. Neurophys., 2004, 91:1748-1762.

Aviel Y, Horn D and Abeles M. Doubly balanced networks of spiking neurons: A memory model with high capacity. NIPS03

Aviel Y, Horn D and Abeles M. Memory Capacity of Balanced networks, Neural Comp., 2004, in press

Hayon G., Abeles M., Lehmann D. Modeling compositionality by dynamic binding of synfire chains. J. Comp. Neurosci. 17:179-201, 2004

Hayon G., Abeles M., Lehmann D. A model for representing the dynamics of a system of synfire chains. J. Comp. Neurosci. 18: 41-53, 2005.

Stark E., Abeles M. Applying resampling methods to neurophysiological data. J. Neurosci. Methods, 2005, in Press

 

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